oral and injectable steroids

An in-depth analysis of the advantages and drawbacks of oral and injectable steroids is provided.


Almost every steroid user has pondered the same issue at some point in his or her life: “Should I use oral steroids or injectable steroids?”.

For many beginners, injectable steroids are a turnoff, whether it is due to a fear of needles, an inability to inject efficiently, or just because it is a pain in the buttocks to administer (excuse the pun).

Is it true that injectable steroids are safer for users than oral steroid medications?

It is true that orals are as bad as they have been made out to be by the media and the public.

Here, we will explore the pros and drawbacks of oral steroids vs injectable steroids so that you will be informed of what to expect and which method of administration is most appropriate for you.

Oral Steroids

oral steroids


  • Dianabol
  • Anadrol
  • Anavar
  • Winstrol
  • Primobolan (Methenolone Acetate)
  • Testosterone Undecanoate
  • Halotestin
  • Turinabol

Oral Steroids Pros

Basic and easy to take

Taking oral steroids (pills) is a fairly handy method of treatment. Everything is as simple as swallowing a pill with water and being on your way. In addition, you will not have to worry about the liver breaking down the substance and rendering it useless since the majority of popular orals are c17-alpha alkylated, which means that a significant portion of the chemical will survive liver metabolism.

Results in a Short Time

Due to oral steroids’ shorter half-lives compared to injectable steroids, they will begin to work more quickly and provide benefits within a few days. For example, when testosterone undecanoate is administered, serum testosterone levels in the bloodstream peak 5 hours after the drug is administered. Therefore, orals need greater frequency of administration in order to maintain high amounts of persistent exogenous testosterone in the body.

Detection time is reduced

Due to the fact that oral steroids are often detected for a shorter period of time than injectable steroids, oral steroids are preferable if you want to avoid being tagged for a drug test and want all substances to leave your system as quickly as possible.
The following table compares the detection time of oral steroids to that of injectable steroids.

Oral SteroidsDetection TimeInjectable SteroidsDetection Time
Winstrol3 WeeksWinstrol Depot9 Weeks
Anavar3 Weeks Testosterone Enanthate3 Months
Primobolan5 Weeks Testosterone Cypionate3 Months
Andriol5 Weeks Sustanon 2503 – 4 Months
Dianabol6 Weeks Trenbolone Scetate5 Months
Anadrol8 WeeksDeca Durabolin18 Months

In other cases, this rule does not apply, like in the case of injectable steroids such as testosterone suspension, which may be detected in as little as two to three days.

Oral Steroids Cons

It is bad for your heart.

Oral steroids are often more harmful to the heart than injectable steroids, owing to the fact that they drop HDL cholesterol levels more than injectable steroids. HDL is a healthy cholesterol score that, when high, may help to reduce blood pressure, while low levels can cause it to rise.

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Hepatic lipase is an enzyme present in the liver that is responsible for reducing HDL cholesterol. Many oral drugs have the effect of increasing hepatic lipase.

Because of their unfavorable effects on both HDL cholesterol and LDL cholesterol levels, anabolic steroids such as anadrol and dianabol, as well as winstrol, are among the most dangerous anabolic steroids for cardiovascular health.

Because of this, if your major concern is maintaining good heart health while taking steroids and keeping your blood pressure under control, injectable steroids (particularly testosterone) are the best option for your requirements.

However, this does not rule out the possibility of injectable steroids causing high blood pressure, since they very well may; this is especially true if the drug in issue is exceptionally strong (such as trenbolone).

Dangerous for the liver.

It is also true that oral drugs are hepatotoxic, which means that they stress the liver, as shown by a rise in levels of the liver enzymes ALT and AST. Some bodybuilders are not very worried about this side effect since the liver often cures itself after a cycle and has excellent self-healing abilities in its own right. Others, on the other hand, are.

In order to err on the side of caution while using orals, bodybuilders often supplement with TUDCA, which is a liver support supplement. Furthermore, it is not recommended to stack hepatotoxic steroids together, such as dianabol and anadrol, since doing so may result in liver damage in certain individuals.

It should be noted that there are certain exceptions to this tendency, with some orals, such as anavar and testosterone undecanoate, not causing serious liver damage; these are the exceptions to the rule.

Anavar’s hepatic effects are moderate since the kidneys are working hard to process the anabolic steroid oxandrolone, which relieves stress on the liver. testosterone undecanoate, on the other hand, causes no danger since it fully bypasses the liver and is absorbed by the lymphatic system.

Aspects of Biological Importance.

It is possible that the biological availability of oral steroids will be significantly decreased when compared to injectable steroids if they are used incorrectly.

Take, for example, oral steroids, which should not be taken with a high-fat meal due to the fact that many of the tablets are fat-soluble in nature. Therefore, in order to get the most advantages from oral steroids, they should be taken with meals whenever possible.

The only exception to this guideline is testosterone undecanoate (commonly known as Testocaps or Andriol), which should be taken with a high-fat meal (containing at least 19 grams of fat) in order to get the best benefits possible.

Injectable Steroids

injectable steroids


  • Trenbolone
  • Winstrol Depot
  • Deca Durabolin
  • Testosterone
  • Equipoise
  • Primobolan (Methenolone Enanthate)

Intramuscular injections of injectable steroids are used to deliver the hormones deep into the muscle tissue. However, they are frequently done on the buttocks or outer thigh region.


Less Liver Toxic

According to popular belief, injectable steroids do not put a strain on the liver. However, they do have some toxicity, and in rare situations of steroid misuse, they may result in liver failure. Despite the fact that they enter the bloodstream quickly, it is thought that they transit via the liver before exiting the body completely. However, the strain is far reduced when compared to orals, and as a result, it is not regarded as a problem.

Since injectables are only used intermittently, most bodybuilders would not consider taking a liver support medication (such as TUDCA or milk thistle).

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Better for the Heart

Given that all steroids are derivatives of exogenous testosterone, all of them will raise blood pressure, resulting in an increase in LDL cholesterol and a decrease in HDL cholesterol.

But since they do not activate hepatic lipase, an enzyme that has already been discussed as being detrimental to the cardiovascular system, injectable steroids are thought to be less harmful to the cardiovascular system. As a result, injectable steroids may induce less plaque build-up in the arteries as compared to oral steroids.


Incorrect Injections Have the Potential to Be Fatal

It is possible to suffer from septic shock or nerve damage if a user injects into the incorrect spot with their needle. These are very dangerous consequences that might result in permanent disability or death. Since oil-based steroids are administered intravenously, it is critical that users understand how to inject appropriately.

Common Intramuscular injection sites:

  • Buttocks
  • Outer thigh

Dr. Nabil Ebraheim performs a proper intramuscular injection into the buttocks, as seen in the graphic and video example provided below.

An example of a proper intramuscular injection into the outer thigh is shown in the video below.

Risk of HIV

Individuals contracting HIV by sharing needles is one of the most common reasons for this to happen.

When a person injects themself, some of their blood will remain in the syringe after they have finished injecting (and needle). As a result, while using this mode of administration as opposed to merely taking a tablet, more measures must be taken.


Certain anabolic steroids, such as testosterone propionate, may be uncomfortable to deliver, whilst other anabolic steroids are more comfortable to administer. Muscle soreness is also frequent, and it may be felt deep inside the muscle and continue for many hours or even days after the injury.


When giving steroids, especially trenbolone, a strong dry cough is typical — a feeling known as ‘tren cough’ — which is characterized by a dry, hacking cough. This response happens when the oil comes into contact with a blood vessel, resulting in severe coughing that lasts for several seconds. When injecting, this is a frequent response that occurs around 1 out of every 5 times. Despite the fact that it is a frightening experience for newcomers, this is not a hazardous side effect.

When oil comes into contact with a vessel, foreign metabolites enter the lungs, causing the body to cough as a self-defense strategy to eliminate the compounds that have entered. As a consequence, there is a metallic taste on your tongue.

Due to the fact that trenbolone is an irritant to the lungs, it is more likely when it is administered intravenously. This is similar to how cayenne pepper is an irritant to the skin.


administered intravenously and orally

Will Injectable Steroids Generate Better Gains than Oral Steroids?

As they do not need to travel through the liver, injectable steroids may theoretically provide greater gains than oral steroids because their biological availability is higher than that of oral steroids.

However, this does not seem to be the case in real life, where orals appear to be just as effective (if not more so in some examples).

Despite the fact that orals have lower biological availability, research has shown that they may have an impact on how a molecule is used by the body. For example, orals have the ability to affect tissue selectivity and hepatic IGF 1 release, which entirely alters the chemistry of the substance; as a consequence, users’ outcomes might be more or less dependent on the molecule.

Aside from these changes, the anabolic, androgenic, progesterone and estrogenic scores may also alter according to the mode of administration; this is also true for the half-lives/detection times (as already discussed).

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The most potent oral steroid is referred to be…

All three of these oral steroids (Anavar, Primobolan (methenolone acetate), and testosterone undecanoate) are regarded to be rather safe in most cases.

There is one thing that all three of these substances have in common, and that is that they are all quite expensive.

Among oral steroids, testosterone undecanoate is the most secure alternative for bulking up and striving to gain muscle mass while maintaining a healthy weight.

In terms of safety, Anavar and Primobolan are the most effective oral steroids to utilize when cutting and seeking to reduce your body fat percentage while also gaining some lean muscle mass.

Any of these steroids will not cause a significant rise in your sign, and testosterone suppression will be modest (unless in the case of testosterone undecanoate). Furthermore, none of these steroids will cause liver damage, which is quite improbable.

When using oral drugs, is it possible to mix them with injectables?

Without a doubt, the answer is yes. Cycles that contain orals and injectables are among the most frequent, and they include the following options:

In addition to Dianabol and Deca, Anadrol and Winstrol, and Anavar and Testosterone are also available.
However, due to the risk of liver damage, some bodybuilders who are comfortable injecting (and have done so for years) may naturally move away from the usage of oral supplements.

Despite this preference, orals should not be considered dangerous if they are taken in little doses and over a short period of time.

Typically, oral drugs are only considered a priority when they are used in exceptionally large doses or when users do not take sufficient time off between cycles. As a general rule of thumb, the length of time you spend on steroids should be proportional to the amount of time you spend off steroids. As a result, in order to maintain optimal health, the latter should dominate the former.

Steroids that are administered intravenously and orally.

For the same reason that injectable steroids are not seen as ‘better’ than oral steroids, the same is true in the opposite way.

It is necessary to examine each chemical on its own merits, both in terms of results and side effects, in order to determine whether or not it is worthwhile to take it on.

In order to avoid liver problems, for example, you would take testosterone (injectable) or Andriol (oral) — and you would have no trouble doing so.

However, it is acceptable to assert that injectable steroids are more beneficial to the central nervous system and liver than orally administered steroids (on average).

Despite the fact that trenbolone is one of the most difficult anabolic steroids accessible and that it is an injectable, it is still considered a mild anabolic steroid.

Similarly, if your goal is to take steroids to improve your athletic performance and you know you will be submitted to a drug test soon, it could be a good idea to use oral steroids instead of injectable steroids since they need a shorter detection time.

Whether you choose oral or injectable steroids, the kind of steroid you use will be decided by your specific goals.

To summarize: carry out your research. If you want to use oral meds, make sure your liver and heart are in perfect operating condition before beginning. TUDCA and animal oil should be taken in conjunction for the most efficient protection possible.

Aside from that, it is generally not a good idea to take many oral drugs at the same time since this might place additional strain on the liver.

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